Technical note: The effect of the 4-mm-collimator output factor on gamma knife dose distributions

John P. Gibbons, Dimitris Mihailidis, Curtis Worthington, Hassaan Alkhatib, Raleigh Boulware, Robert Clark, Burke Dial, William Neglia

Abstract


We present results of investigations of the clinical significance of variations in the value of the 4-mm-collimator output factor, OF4/18. Changes in treatment volume, dose-volume histograms (DVHs), and isodose distributions were studied, by varying OF4/18 up to 20. The variations were performed on a sample of clinical patient treatment plans for which the 4 mm collimator was used. Although smaller effects are noted for the prescription isodose line, greater dosimetric changes occur for higher dose regions within the target. 2003 American College of Medical Physics.

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